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Contributor Information

  • Institute The Institute of Cancer Research

Tool Details

  • Tool name: Anti-KSV CyclinD [94B]
  • Clone: 94B
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Virus
  • Host: Rat
  • Cancer type: Skin cancer; Blood cancer
  • Application: IHC ; IF ; IP ; WB
  • Description: HHV8 is associated with the develpment of Kaposi's Sarcoma and a number of B cell lymphomas in AIDS patients. HHV8 encodes a viral (v) cyclin homologous to cellular D type cyclins, a class of positive cell cycle regulators that are physiologically modulated by the p27(Kip1) cell cycle inhibitor.
  • Isotype: IgG
  • Research area: Microbiology

  • For Research Use Only

Target Details

  • Target: Kaposi's Sarcoma Virus D-type cyclin
  • Target background: HHV8 is associated with the develpment of Kaposi's Sarcoma and a number of B cell lymphomas in AIDS patients. HHV8 encodes a viral (v) cyclin homologous to cellular D type cyclins, a class of positive cell cycle regulators that are physiologically modulated by the p27(Kip1) cell cycle inhibitor.

Application Details

  • Application: IHC ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Platt et al. 2000. Virology. 272(2):257-66. PMID: 10873769.
  • •  Detection of the human herpesvirus 8-encoded cyclin protein in primary effusion lymphoma-derived cell lines.