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Contributor Information

  • Name Julian Gannon
  • Institute Cancer Research UK, London Research Institute: Clare Hall Laboratories

Tool Details

  • Tool name: Anti-FZR1 [AR38.2]
  • Alternate names: Fizzy/Cell Division Cycle 2 Related 1; CDC2-Like Protein 1; Cdh1/Hct1 Homolog; CDC2 Homolog 1; HCDH1; CDH1; FZR; CDC2-Like 1b; KIAA1242; CDC2C; FZR2; HCDH; FYR
  • Clone: AR38.2
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human ; Mouse
  • Host: Mouse
  • Application: ELISA ; WB
  • Strain: Balb/c
  • Description: FZR1 is related to Fizzy protein (Cdc20). Both FZR1 and Cdc20 are activators of the anaphase promoting complex (APC), which is responsible for the destruction of many cell cycle related proteins.
  • Immunogen: His-tagged recombinant Fizzy Related Protein (also known as Cdh1)
  • Isotype: IgG1
  • Research area: Cell biology; Biochemistry
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: Fizzy Related Protein (FZR1, Cdh1)
  • Target background: FZR1 is related to Fizzy protein (Cdc20). Both FZR1 and Cdc20 are activators of the anaphase promoting complex (APC), which is responsible for the destruction of many cell cycle related proteins.

Application Details

  • Application: ELISA ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Holt et al. 2010. Development. 137(8):1297-304. PMID: 20223764.
  • •  Spatial regulation of APCCdh1-induced cyclin B1 degradation maintains G2 arrest in mouse oocytes.