ANTIBODIES
Contributor Information
- Institute Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
- Tool name: Anti-ORC1 [ORC1 7F6/1]
- Clone: ORC1 7F6/1
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Molecular weight of the target: 45-97 kDa
- Application: IP ; ChIP ; ELISA ; IHC ; IP ; WB ; ChIP-seq
- Strain: Balb/c
- Description: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
- Immunogen: Bacterially expressed Human ORC1
- Isotype: IgG1
- Research area: Genetics
- Myeloma used: Sp2/0-Ag14
- For Research Use Only
Target Details
- Target: ORC1
- Target molecular weight: 45-97 kDa
- Target background: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
Application Details
- Application: IP ; ChIP ; ELISA ; IHC ; IP ; WB ; ChIP-seq
Handling
- Format: Liquid
- Concentration: 0.76 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15Ă°C to -25Ă°C
- Shipping conditions: Shipping at 4Ă°C
Documentation
References
- • Lu et al. 2016. Biol Open. 5(10):1449-1460. PMID: 27744293.
- • Beck et al. 2012. Genes Dev. 26(23):2580-9. PMID: 23152447.
- • Salsi et al. 2009. Mol Cell Biol. 29(21):5775-88. PMID: 19703996.
- • Burke et al. 2001. J Biol Chem. 276(18):15397-408. PMID: 11278932.
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