ANTIBODIES

Contributor Information
- Name Peter Beverley
- Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
- Tool name: Anti-LewisX [TG-1]
- Alternate names: Fucosyltransferase 4; Galactoside 3-L-Fucosyltransferase; ELAM-1 Ligand Fucosyltransferase; FUC-TIV; FCT3A; ELFT; Stage-Specific Embryonic Antigen; Alpha (1,3) Fucosyltransferase; EC 2.4.1.65; Lewis X; SSEA-1; FUTIV; CD15; LeX
- Clone: TG-1
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Molecular weight of the target: 156 kDa
- Application: FACS ; IHC ; IF
- Strain: CBA
- Description: TG-1 is useful for the differentiation of human leukocytes.
- Immunogen: Thymocyte glycoprotein fraction adsorbed to Con A and eluted with 0.1M glucose.
- Isotype: IgM
- Research area: Cancer; Immunology
- Myeloma used: P3/NS1/1-Ag4.1
- For Research Use Only
Target Details
- Target: Lewis X (CD15)
- Target molecular weight: 156 kDa
- Target background: Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias and is commonly used in the diagnosis of Hodgkin's disease.
Application Details
- Application: FACS ; IHC ; IF
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15ðC to -25ðC
- Shipping conditions: Shipping at 4ðC
Related Tools
References
- • Cho et al. 2010. J Proteome Res. 9(11):5960-8. PMID: 20858014.
- • Sialylated Lewis x antigen bearing glycoproteins in human plasma.
- • Hogg et al. 1984. Immunology. 53(4):753-67. PMID: 6389324.
- • Monoclonal antibodies specific for human monocytes, granulocytes and endothelium.
- • Linch et al. 1984. Blood. 63(3):566-73. PMID: 6365201.
- • Monoclonal antibodies differentiating between monocytic and nonmonocytic variants of AML.
- • Beverley et al. 1980. Nature. 287(5780):332-3. PMID: 7421991.
- • Isolation of human haematopoietic progenitor cells using monoclonal antibodies.