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Contributor Information

  • Name Joyce Taylor-Papadimitriou
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-INFa [ST29]
  • Clone: ST29
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target: 18-25 kDa
  • Application: ELISA ; Fn
  • Strain: Balb/c
  • Description: ST29 distinguishes between sub-species of human INFa and can be used to detect INF oligomers. Neutralises anti-viral activity of INF.
  • Immunogen: Human interferon (HuIFN) produced by Namalwa cells (HuIFN-aN)
  • Isotype: IgG1
  • Research area: Microbiology
  • Myeloma used: P3X63Ag8.653

  • For Research Use Only

Target Details

  • Target: Interferon alpha (INFa)
  • Target molecular weight: 18-25 kDa
  • Target background: INFa is a type I interferon that is involved in the innate immune response against viral infections.

Application Details

  • Application: ELISA ; Fn

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Doganay et al. 2017. Integr Biol (Camb). 9(11):857-867. PMID: 29098213.
  • •  Gainey et al. 2008. J Virol. 82(19):9369-80. PMID: 18667520.
  • •  A hyperfusogenic F protein enhances the oncolytic potency of a paramyxovirus simian virus 5 P/V mutant without compromising sensitivity to type I interferon.
  • •  Shearer et al. 1984. J Immunol. 133(6):3096-101. PMID: 6491281.
  • •  Monoclonal antibodies that distinguish between subspecies of human interferon-alpha and that detect interferon oligomers.