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Contributor Information

  • Name Walter Bodmer
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-Epithelia [PR 4D1]
  • Clone: PR 4D1
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: IHC
  • Strain: Balb/c
  • Description: PR 4D1 may be useful for histological diagnosis of colon disorders. Wide reactivity with GI tract. Reacts with a high MW glycoprotein in human colonic mucus, epithelial cells and cell membranes.
  • Immunogen: Mucosal scrapings and membrane preparations from normal colorectal epithelium and possibly booster inoculations with the colon carcinoma cell line HT29.
  • Isotype: IgG1
  • Research area: Cell biology; Cell signaling and signal transduction
  • Myeloma used: P3/NS1/1-Ag4.1

  • For Research Use Only

Target Details

  • Target: Epithelia (colonic)

Application Details

  • Application: IHC

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   Richman et al. 1987. Int J Cancer. 39(3):317-28. PMID: 2434440.
  •   Monoclonal antibodies to human colorectal epithelium: markers for differentiation and tumour characterization.