ANTIBODIES

Contributor Information
- Name Walter Bodmer
- Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
- Tool name: Anti-Epithelia [PR 4D1]
- Clone: PR 4D1
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: IHC
- Strain: Balb/c
- Description: PR 4D1 may be useful for histological diagnosis of colon disorders. Wide reactivity with GI tract. Reacts with a high MW glycoprotein in human colonic mucus, epithelial cells and cell membranes.
- Immunogen: Mucosal scrapings and membrane preparations from normal colorectal epithelium and possibly booster inoculations with the colon carcinoma cell line HT29.
- Isotype: IgG1
- Research area: Cell biology; Cell signaling and signal transduction
- Myeloma used: P3/NS1/1-Ag4.1
- For Research Use Only
Related Tools
References
- • Richman et al. 1987. Int J Cancer. 39(3):317-28. PMID: 2434440.
- • Monoclonal antibodies to human colorectal epithelium: markers for differentiation and tumour characterization.