ANTIBODIES
Contributor Information
- Name Lionel Crawford
- Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields
- Primary citation Leppard et al. 1983. EMBO J. 2(9):1457-64. PMID: 11892796.
Tool Details
- Tool name: Anti-p53 [Pab 1103]
- Clone: Pab 1103
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Cancer type: Broadly Applicable
- Molecular weight of the target: 53 kDa
- Application: IHC ; IP ; WB
- Strain: Balb/c
- Description: Pab 1103 is an antibody developed against p53, Pab 1103 has an affinity for p53 associated with large T cell.
- Immunogen: A slice of gel containing p53 homogenised in PBS. The p53 was extracted from the human SV40-transformed fibroblast cell line SV80 and purified by immunoprecipitation and SDS gel electrophoresis.
- Isotype: IgM
- Research area: Apoptosis and autophagy; Cancer; Cell biology; Genetics
- For Research Use Only
Target Details
- Target: p53. Large T-associated form of p53
- Target molecular weight: 53 kDa
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Target background: p53 is a stress-regulated transcription factor that regulates cell cycle arrest and was first identified as an SV40 large T antigen-binding protein. Mutation of p53 is the most common genetic change so far identified in a number of major carcinomas.
Pab 1103 is an antibody developed against p53, Pab 1103 has an affinity for p53 associated with large T cell.
Application Details
- Application: IHC ; IP ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15°C to -25°C
- Shipping conditions: Shipping at 4°C
Documentation
Related Tools
References
- • Leppard et al. 1984. J Virol. 50(2):457-64. PMID: 6323746.
- • Leppard et al. 1983. EMBO J. 2(9):1457-64. PMID: 11892796.
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