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Contributor Information

  • Name Clive Dickson
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-FGF3 [MSD1]
  • Clone: MSD1
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human ; Mouse ; Xenopus laevis
  • Host: Mouse
  • Molecular weight of the target: 27 kDa
  • Application: IHC ; IF ; IP ; WB
  • Strain: Balb/c
  • Description: Monoclonal antibody directed against FGF-3, key for investigating breast carcinogenesis resulting from MMTV.
  • Immunogen: Peptide conjugated to BSA.
  • Immunogen UniProt ID: P11487
  • Isotype: IgG2a
  • Research area: Cancer; Tissue-specific biology; Cell signaling and signal transduction; Microbiology
  • Myeloma used: P3/NS1/1-Ag4.1

  • For Research Use Only

Target Details

  • Target: Fibroblast Growth Factor-3 (FGF3; Int2)
  • Target molecular weight: 27 kDa
  • Target background: Monoclonal antibody directed against FGF-3, key for investigating breast carcinogenesis resulting from MMTV.

Application Details

  • Application: IHC ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: Store at -20°C frozen. Avoid repeated freeze / thaw cycles
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Cases et al. 2013. J Biol Chem. 288(23):16655-70. PMID: 23592779.
  • •  Cubilin, a high affinity receptor for fibroblast growth factor 8, is required for cell survival in the developing vertebrate head.
  • •  Vos et al. 2003. J Biol Chem. 278(30):28045-51. PMID: 12732644.
  • •  RASSF2 is a novel K-Ras-specific effector and potential tumor suppressor.
  • •  Antoine et al. 2000. Cell Growth Differ. 11(11):593-605. PMID: 11095248.
  • •  NH2-terminal cleavage of xenopus fibroblast growth factor 3 is necessary for optimal biological activity and receptor binding.