Product Image

Contributor Information

  • Name Walter Bodmer
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-CD1c [M241] mAb
  • Alternate names: CD1c Molecule; CD1C Antigen; C Polypeptide; CD1c Antigen; Differentiation Antigen CD1-Alpha-3; Cortical Thymocyte Antigen; CD1C; BDCA1; CD1A; CD1; R7
  • Clone: M241
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target: 45 kDa
  • Application: IHC ; IP ; RIA
  • Strain: Balb/c
  • Description: M241 is useful for identification and elimination of some leukaemias.
  • Immunogen: MOLT 4 cell line
  • Isotype: IgG1
  • Research area: Cancer; Cell biology; Immunology
  • Myeloma used: P3/NS1/1-Ag4.1

  • For Research Use Only

Target Details

  • Target: CD1c (Human Thymus Leukaemia antigen)
  • Target molecular weight: 45 kDa
  • Target background: Cluster of Differentiation 1c (CD1c) is one of five human CD1 isoforms, a family of b2-microglobulin-associated transmembrane proteins that bind and present lipid antigens to T cells.

Application Details

  • Application: IHC ; IP ; RIA

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

Documentation

Related Tools

Product Image

Anti-Biotin [BK-1/39] rAb

#154806
Product Image

Anti-DNA [m17-s130]

#157801
Product Image

Anti-T-cell receptor mimic against WT p53 [T1-116CR]

#160583

References

  • •  MiR-381-3p Regulates the Antigen-Presenting Capability of Dendritic Cells and Represses Antituberculosis Cellular Immune Responses by Targeting CD1c.
  • •  Wen et al. 2016. J Immunol. :. PMID: 27296666.
  • •  Small et al. 1989. Hum Immunol. 25(3):181-93. PMID: 2670851.
  • •  Characterization of B cells in severe combined immunodeficiency disease.
  • •  Merle-Beral et al. 1988. Eur J Haematol. 41(3):197-203. PMID: 3263283.
  • •  Phenotypic heterogeneity of B- and T-cell differentiation antigens in B-CLL.
  • •  Matsumoto et al. 1986. J Immunol. 137(9):2907-12. PMID: 2428878.
  • •  Fn analysis of activated C1s, a subcomponent of the first component of human complement, by monoclonal antibodies.
  • •  Knowles et al. 1982. Eur J Immunol. 12(8):676-81. PMID: 6754387.
  • •  A monoclonal antibody recognizing a human thymus leukemia-like antigen associated with beta 2-microglobulin.