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Contributor Information

  • Institute Absolute Antibody; University of Oxford

Tool Details

  • Tool name: Anti-Biotin [BK-1/39] rAb
  • Clone: BK-1/39
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Recombinant
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Cancer type: Salivary gland cancer
  • Application: FACS ; IHC ; WB
  • Description: Anti-Biotin antibodies can be used to detect both biotinylated proteins and nucleic acids. Biotin is a water-soluble vitamin, generally classified as a B-complex vitamin. After the initial discovery of biotin, nearly forty years of research were required to establish it as a vitamin. Biotin is required by all organisms but can only be synthesized by bacteria, yeasts, molds, algae, and some plant species.
  • Immunogen: Biotin conjugated to keyhole limpet haemocyanin
  • Isotype: IgG1
  • Research area: Cancer; Cell biology; Cell signaling and signal transduction; Tags and cell markers; Metabolism

  • For Research Use Only

Target Details

  • Target: Biotin
  • Target background: Anti-Biotin antibodies can be used to detect both biotinylated proteins and nucleic acids. Biotin is a water-soluble vitamin, generally classified as a B-complex vitamin. After the initial discovery of biotin, nearly forty years of research were required to establish it as a vitamin. Biotin is required by all organisms but can only be synthesized by bacteria, yeasts, molds, algae, and some plant species.

Application Details

  • Application: FACS ; IHC ; WB

Handling

  • Format: Liquid
  • Storage buffer: PBS (0.1 M) + 0.5 M imidazole at pH 7.4 + 0.05 % ProClin300TM. This product was purified using affinity chromatography (protein A).
  • Shipping conditions: Shipping at 4° C

Documentation

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References

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  • •  Hirokawa et al. 2010. Diagn Cytopathol. 38(12):890-6. PMID: 20091902.
  • •  Immunohistochemical study of the distribution of endogenous biotin and biotin-binding enzymes in ductal structures of salivary gland tumours.
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