ANTIBODIES

Contributor Information
- Institute University of Cambridge
Tool Details
- Tool name: Anti-HPV16L1 [CamVir 1]
- Clone: CamVir 1
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human papilloma virus
- Host: Mouse
- Cancer type: Gynaecologic cancer
- Molecular weight of the target: 56 kDa
- Application: ELISA ; IHC ; IP ; WB
- Description: The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases, and HPV-1, which is associated with benign cutaneous warts. HPV late protein L1 is the major capsid protein.
- Immunogen: A b galactosidase-L1 fusion protein purified by PAGE.
- Isotype: IgG2a
- Research area: Cancer; Microbiology
- Myeloma used: NS0
- For Research Use Only
Target Details
- Target: Human papilloma virus type 16, major capsid protein L1 (HPV16 L1)
- Target molecular weight: 56 kDa
- Target background: The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases, and HPV-1, which is associated with benign cutaneous warts. HPV late protein L1 is the major capsid protein.
Application Details
- Application: ELISA ; IHC ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15ðC to -25ðC
- Shipping conditions: Shipping at 4ðC
Related Tools
References
- • Day et al. 2012. Clin Vaccine Immunol. 19(7):1075-82. PMID: 22593236.
- • A human papillomavirus (HPV) in vitro neutralization assay that recapitulates the in vitro process of infection provides a sensitive measure of HPV L2 infection-inhibiting antibodies.
- • Steele et al. 2005. Br J Cancer. 93(2):248-59. PMID: 15986031.
- • T-cell responses to human papillomavirus type 16 among women with different grades of cervical neoplasia.
- • Zhang et al. 1998. Virology. 243(2):423-31. PMID: 9568041.
- • Expression of human papillomavirus type 16 L1 protein in Escherichia coli: denaturation, renaturation, and self-assembly of virus-like particles in vitro.
- • McLean et al. 1990. J Clin Pathol. 43(6):488-92. PMID: 2166093.
- • Production and characterisation of a monoclonal antibody to human papillomavirus type 16 using recombinant vaccinia virus.