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Contributor Information

  • Institute University of Cambridge

Tool Details

  • Tool name: Anti-HPV16L1 [CamVir 1]
  • Clone: CamVir 1
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human papilloma virus
  • Host: Mouse
  • Cancer type: Gynaecologic cancer
  • Molecular weight of the target: 56 kDa
  • Application: ELISA ; IHC ; IP ; WB
  • Description: The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases, and HPV-1, which is associated with benign cutaneous warts. HPV late protein L1 is the major capsid protein.
  • Immunogen: A b galactosidase-L1 fusion protein purified by PAGE.
  • Isotype: IgG2a
  • Research area: Cancer; Microbiology
  • Myeloma used: NS0

  • For Research Use Only

Target Details

  • Target: Human papilloma virus type 16, major capsid protein L1 (HPV16 L1)
  • Target molecular weight: 56 kDa
  • Target background: The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases, and HPV-1, which is associated with benign cutaneous warts. HPV late protein L1 is the major capsid protein.

Application Details

  • Application: ELISA ; IHC ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   Day et al. 2012. Clin Vaccine Immunol. 19(7):1075-82. PMID: 22593236.
  •   A human papillomavirus (HPV) in vitro neutralization assay that recapitulates the in vitro process of infection provides a sensitive measure of HPV L2 infection-inhibiting antibodies.
  •   Steele et al. 2005. Br J Cancer. 93(2):248-59. PMID: 15986031.
  •   T-cell responses to human papillomavirus type 16 among women with different grades of cervical neoplasia.
  •   Zhang et al. 1998. Virology. 243(2):423-31. PMID: 9568041.
  •   Expression of human papillomavirus type 16 L1 protein in Escherichia coli: denaturation, renaturation, and self-assembly of virus-like particles in vitro.
  •   McLean et al. 1990. J Clin Pathol. 43(6):488-92. PMID: 2166093.
  •   Production and characterisation of a monoclonal antibody to human papillomavirus type 16 using recombinant vaccinia virus.