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Contributor Information

  • Name Walter Bodmer
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-HLA-B7 [BB7.1]
  • Clone: BB7.1
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; FACS
  • Strain: Balb/c
  • Description: This antibody can be used for HLA typing.
  • Immunogen: Papain solubilised HLA-A2, B7
  • Isotype: IgG1
  • Research area: Immunology
  • Myeloma used: P3/NS1/1-Ag4.1

  • For Research Use Only

Target Details

  • Target: HLA-B7
  • Target background: Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D).

Application Details

  • Application: FACS ; FACS

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   Reches et al. 2016. J Immunol. :. PMID: 27194785.
  •   HNRNPR Regulates the Expression of Classical and Nonclassical MHC Class I Proteins.
  •   Dellgren et al. 2015. PLoS One. 10(8):e0135385. PMID: 26258424.
  •   Cell surface expression level variation between two common Human Leukocyte Antigen alleles, HLA-A2 and HLA-B8, is dependent on the structure of the C terminal part of the alpha 2 and the alpha 3 domains.
  •   Rancan et al. 2015. PLoS Pathog. 11(6):e1004906. PMID: 26067064.
  •   Latent Membrane Protein LMP2A Impairs Recognition of EBV-Infected Cells by CD8+ T Cells.
  •   Levering et al. 2000. Cytometry. 42(2):95-105. PMID: 10797446.
  •   External quality assessment of flow cytometric HLA-B27 typing.
  •   Parham et al. 1981. Hum Immunol. 3(4):277-99. PMID: 7035415.
  •   Partial purification and some properties of BB7.2. A cytotoxic monoclonal antibody with specificity for HLA-A2 and a variant of HLA-A28.
  •   Brodsky et al. 1979. Immunol Rev. 47:3-61. PMID: 95015.
  •   Monoclonal antibodies for analysis of the HLA system.