Product Image

Contributor Information

  • Name Jacqueline Hayles
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-Cdc13 [6F11/2]
  • Alternate names: Cell division control protein 13; YDL22C
  • Clone: 6F11/2
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Schizosaccharomyces pombe
  • Host: Mouse
  • Application: WB ; IHC ; IP ; WB
  • Strain: Balb/c
  • Description: 6F11/2 can be used for detecting Cdc13 and associated Cdk1 kinase activation.
  • Immunogen: Full length cdc13
  • Isotype: IgG2a
  • Research area: Genetics
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: Cell-division cycle protein 13 (cdc13)
  • Target background: Cdc13 is a fission yeast (S. pombe) B-type M-phase cyclin. Cdc13 binds to Cdk1 (cdc2), and the resulting Cdk1-Cdc13 complex controls the G2/M transition of the cell cycle.

Application Details

  • Application: WB ; IHC ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

Related Tools

Product Image

Anti-cancer inhibitor of protein phosphotase 2A [4A9-1A2]

#158414
Product Image

Anti-Omomyc [21-1-3]

#153657
Product Image

Anti-FANCC [R7237]

#154179

References

  • •  Rothe et al. 2017. J Cell Sci. 130(23):4028-4037. PMID: 29046339.
  • •  Koch et al. 2012. ACS Chem Biol. 7(4):723-31. PMID: 22264160.
  • •  A chemical genetic approach for covalent inhibition of analogue-sensitive aurora kinase.
  • •  Okuzaki et al. 2010. Cell Cycle. 9(18):3751-60. PMID: 20855961.
  • •  Spo5 phosphorylation is essential for its own timely degradation and for successful meiosis in Schizosaccharomyces pombe.
  • •  Decottignies et al. 2001. J Cell Sci. 114(Pt 14):2627-40. PMID: 11683390.
  • •  In vivo localisation of fission yeast cyclin-dependent kinase cdc2p and cyclin B cdc13p during mitosis and meiosis.