Product Image

Contributor Information

  • Name Stephen West
  • Institute Cancer Research UK, London Research Institute: Clare Hall Laboratories

Tool Details

  • Tool name: Anti-RuvB [RuvB 4G5/1]
  • Clone: RuvB 4G5/1
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: E.coli
  • Host: Mouse
  • Molecular weight of the target: 37 kDa
  • Application: ELISA ; IHC ; IP ; RIA ; WB
  • Strain: Balb/c
  • Description: During genetic recombination and post replication repair of DNA damage, RuvA and RuvB (a helicase) act in a complex to promote branch migration of Holliday junctions and RuvC (an endonuclease) cleaves Holliday junctions.
  • Immunogen: Ruv B protein from E. Coli
  • Isotype: IgG1
  • Research area: Microbiology; Genetics
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: Ruv B protein
  • Target molecular weight: 37 kDa
  • Target background: During genetic recombination and post replication repair of DNA damage, RuvA and RuvB (a helicase) act in a complex to promote branch migration of Holliday junctions and RuvC (an endonuclease) cleaves Holliday junctions.

Application Details

  • Application: ELISA ; IHC ; IP ; RIA ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

Related Tools

Product Image

Anti-MHC II [BU26]

#153215
Product Image

Anti-O-linked N-acetylglucosamine (O-GlcNAc) [6B5.A8]

#153901
Product Image

Anti-Leu1 [Y2/178]

#151344

References

  • •  Davies et al. 1998. Curr Biol. 8(12):725-7. PMID: 9637927.
  • •  Formation of RuvABC-Holliday junction complexes in vitro.
  • •  Eggleston et al. 1997. Cell. 89(4):607-17. PMID: 9160752.
  • •  In vitro reconstitution of the late steps of genetic recombination in E. coli.