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Contributor Information

  • Name Nancy Hogg
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-LewisX [28]
  • Alternate names: Fucosyltransferase 4; Galactoside 3-L-Fucosyltransferase; ELAM-1 Ligand Fucosyltransferase; FUC-TIV; FCT3A; ELFT; Stage-Specific Embryonic Antigen; Alpha (1,3) Fucosyltransferase; EC 2.4.1.65; Lewis X; SSEA-1; FUTIV; CD15; LeX
  • Clone: 28
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target: 83 kDa
  • Application: IHC ; IP ; FACS ; IHC ; IP
  • Strain: Balb/c
  • Description: Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias and is commonly used in the diagnosis of Hodgkin’s disease. It can also be used for analysis of myeloid leukaemias and studies of myeloid differentiation.
  • Immunogen: Monocytes, separated from other peripheral blood leucocytes (PBL) on fibronectin plates.
  • Isotype: IgM
  • Research area: Cancer; Immunology
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: Lewis X (CD15)
  • Target molecular weight: 83 kDa
  • Target background: Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias and is commonly used in the diagnosis of Hodgkin's disease. It can also be used for analysis of myeloid leukaemias and studies of myeloid differentiation.

Application Details

  • Application: IHC ; IP ; FACS ; IHC ; IP

Handling

  • Format: Liquid
  • Concentration: 0.71 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -80°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Hogg et al. 1984. Immunology. 53(4):753-67. PMID: 6389324.
  • •  Monoclonal antibodies specific for human monocytes, granulocytes and endothelium.
  • •  Linch et al. 1984. Blood. 63(3):566-73. PMID: 6365201.
  • •  Monoclonal antibodies differentiating between monocytic and nonmonocytic variants of AML.