ANTIBODIES
Contributor Information
- Name Nancy Hogg
- Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
- Tool name: Anti-Vascular endothelium [10]
- Clone: 10
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: IHC
- Strain: Balb/c
- Description: Monoclonal antibody which specifically binds vascular endothelium tissue.
- Immunogen: Fibronectin-purified human monocytes.
- Isotype: IgM
- Research area: Cancer; Tissue-specific biology; Cell biology
- Myeloma used: Sp2/0-Ag14
- For Research Use Only
Target Details
- Target: Vascular endothelium marker
- Target background: The vascular endothelium comprises the thin inner layer of cells lining arteries and veins, with an essential role in the regulation of blood vessel tone and cellular activity. This antibody may be used to study the synovial membrane in rheumatoid, osteoarthritic and traumatised joints as well as normal vasculature. Anti-vascular endothelium (10) reactivity is stronger on capillary endothelium and weaker on larger arteries and veins.
Application Details
- Application: IHC
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: Store at -20Ă°C frozen. Avoid repeated freeze / thaw cycles
- Shipping conditions: Shipping at 4Ă°C
Documentation
Related Tools
References
- • Palmer et al. 1985. Clin Exp Immunol. 59(3):529-38. PMID: 3886218.
- • Features of synovial membrane identified with monoclonal antibodies.
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