CELL LINES

Contributor Information
- Name Mikhail Alexeyev
- Institute University of South Alabama
Tool Details
- Tool name: HT-22 rho-0 Cell Line
- Tool type: Cell Lines
- Parental cell line: HT-22
- Organism: Mouse
- Tissue: Brain
- Disease: Mitochondrial Disease
- Conditional: No
- Description: Derived from the HT-22 murine hippocampal neuronal cell line, these cells lack mitochondrial DNA (mtDNA) and can be repopulated with exogenous mtDNA (e.g., mtDNA from patients with mitochondrial disease) allowing for mitochondrial mutational analysis. The original parental lines are available upon request.
- Research area: Genetics; Drug development; Metabolism
- For Research Use Only