CELL LINES
Contributor Information
- Name Mikhail Alexeyev
- Institute University of South Alabama
Tool Details
- Tool name: A549p0#1a Cell Line
- Tool type: Cell Lines
- Parental cell line: A549
- Organism: Human
- Tissue: Lung
- Disease: Mitochondrial Disease
- Conditional: No
- Description: Derived from A549 human lung adenocarcinoma cell line, these cells lack both mitochondrial DNA (mtDNA) and a functional mitochondrial electron transport chain and are auxotrophic for uridine and pyruvate. These cells can be repopulated with exogenous mtDNA (e.g., mtDNA from patients with mitochondrial disease) allowing for mitochondrial mutational analysis. The original parental lines are available upon request.
- Research area: Genetics; Drug development; Metabolism
- For Research Use Only
Target Details
Application Details
Handling
- Format: Frozen
- Shipping conditions: Dry ice
Documentation
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