CELL LINES
Contributor Information
- Name Alison Quayle
- Institute Louisiana Sate University (LSU) Health Sciences Center New Orleans
Tool Details
- Tool name: A2EN human epithelial cell line
- Tool type: Cell Lines
- Organism: Human
- Tissue: Cervix
- Model: Immortalised Line
- Description: A2EN is an immortalized epithelial cell line originating from an endocervical tissue explant that can be polarized to exhibit distinct apical and basolateral membrane domains. Polarized A2EN cells maintain phenotypic and functional characteristics of the epithelial endocervix cells including secreting mucus and expressing MUC5B, hormone receptors, anti-microbial peptides (AMPs) and pro-inflammatory cytokines and chemokines. This in vitro model can be used in sexually transmitted infections and topical microbicides research.
- Research area: Reproductive Biology
- For Research Use Only
Target Details
Application Details
Handling
- Format: Frozen
- Shipping conditions: Dry ice
Documentation
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