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Contributor Information

  • Name Thorbald Van Hall
  • Institute Leiden University and Leiden University Medical Center; Stichting Oncode Institute

Tool Details

  • Tool name: P815.Trh4 cells
  • Tool type: Cell Lines
  • Tool sub-type: Continuous
  • Parental cell line: P815
  • Organism: Mouse
  • Tissue: Bone Marrow
  • Cancer type: Mouse mast cell neoplasm
  • Disease: Cancer
  • Model: Tumour line
  • Description: This cell line provides a model to help to understand T-cell recognition through Trh4 expression. ER-resident ceramide synthase Trh4 is a prototypic example of a neo-antigen selectively presented by cells through various pathways. The P815 cell line has been made to over-express Trh4 and can be utilised to understand this peptide presentation process.
  • Research area: Cancer
  • Production details: Retroviral transduction of the mouse Trh4 gene in an IRES-GFP construct
  • Cellosaurus ID: CVCL_2154

  • For Research Use Only

Target Details

  • Target: Trh4

Application Details

Handling

  • Format: Frozen
  • Storage conditions: Liquid Nitrogen
  • Shipping conditions: Dry ice
  • Mycoplasma free: Yes
  • Biosafety level: 1

Documentation

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References

  • •  Oliveira et al. 2011. Eur J Immunol. 41(11):3114-24. PMID: 21898382.