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Contributor Information

  • Name Dr. Francisco RuĂ­z-Cabello Osuna,Dr. Miguel Ángel LĂłpez-Nevot and Federico Garrido Torres-Puchol,
  • Institute Virgen de las Nieves University Hospital, The Andalusian Health Service
  • Primary citation Pichuantes et al. 1997. Tissue Antigens. 50(3):265-276. PMID: 9331949

Tool Details

  • Tool name: Anti-CD105 monoclonal antibody [GRE]
  • Clone: GRE
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target: 170-180 kDa
  • Application: FACS; IHC; ELISA; WB
  • Description: The CD105 antigen, also called endoglin, is a 170-180 kDa RGD-containing molecule present on the cell surface as a disulfide-linked homodimer. The molecule is a co-receptor for growth and transformation factor (TGF) b1 and b3. It is expressed primarily on endothelial cells, but also appears strongly on B-prelymphocytes and a subpopulation of monocytes. CD105 is a regulatory protein of the TGF-beta receptor complex.
  • Immunogen: KM3 cell line
  • Isotype: IgG1
  • Research area: Cell signalling

  • For Research Use Only

Target Details

  • Target: CD105
  • Target molecular weight: 170-180 kDa

Application Details

  • Application: FACS; IHC; ELISA; WB

Handling

  • Storage buffer: PBS with 0.02% azide
  • Storage conditions:  -15°C to -25°C
  • Shipping conditions: 4°C

Documentation

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References

  • •  Pichuantes et al. 1997. Tissue Antigens. 50(3):265-276. PMID: 9331949