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Contributor Information

  • Name Dr. Francisco RuĂ­z-Cabello Osuna,Dr. Miguel Ángel LĂłpez-Nevot and Federico Garrido Torres-Puchol,
  • Institute Virgen de las Nieves University Hospital, The Andalusian Health Service
  • Primary citation Ruiz-Cabello. 1985. Sangre (Barc). 30(2):190-196. PMID: 3859940

Tool Details

  • Tool name: Anti-HLA-DR monoclonal antibody [GRB1]
  • Clone: GRB1
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Reactivity: Human
  • Host: Mouse
  • Cancer type: Blood cancer
  • Molecular weight of the target: 35 kDa & 33 kDa (68 kDa; heterodimer)
  • Application: FACS; IHC; ELISA; WB
  • Description: HLA-DR antigen is composed of an alpha-beta heterodimer of 35 and 33 Kd respectively. It is highly polymorphic in the human population. GRB1 recognises an epitope shared by all HLA-DR alleles. It is expressed in antigen presenting cells: dendritic cells, macrophages and B lymphocytes and in some tumours
  • Immunogen: B-ALL cells
  • Isotype: IgG2ak
  • Research area: Cancer

  • For Research Use Only

Target Details

  • Target: HLA-DR
  • Target molecular weight: 35 kDa & 33 kDa (68 kDa; heterodimer)

Application Details

  • Application: FACS; IHC; ELISA; WB

Handling

  • Storage buffer: PBS with 0.02% azide
  • Storage conditions:  -15°C to -25°C
  • Shipping conditions: 4°C

Documentation

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References

  • •  Ruiz-Cabello. 1985. Sangre (Barc). 30(2):190-196. PMID: 3859940