Product Image

Contributor Information

  • Name Fumio Takei
  • Institute BC Cancer

Tool Details

  • Tool name: Anti-LY-49A [YE1/48.10.6]
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Mouse
  • Host: Rat
  • Molecular weight of the target: 44 kDa
  • Application: IP ; FACS
  • Description: The Ly-49A is a 44 kDa, type II transmembrane protein with disulfide-linked homodimers and external C-type lectin domains. Ly-49A is present on the surface of mouse NK cells with the purpose to inhibit NK cell activation by recognition and interaction with certain MHC-1s on target cells. The Ly-49A receptor recognizes H-2Dd and H-2Dk.
  • Immunogen: ECA17.9.8 cells
  • Research area: Immunology; Cancer
  • Myeloma used: Y3

  • For Research Use Only

Target Details

  • Target: Ly-49A
  • Target molecular weight: 44 kDa
  • Target background: The Ly-49A is a 44 kDa, type II transmembrane protein with disulfide-linked homodimers and external C-type lectin domains. Ly-49A is present on the surface of mouse NK cells with the purpose to inhibit NK cell activation by recognition and interaction with certain MHC-1s on target cells. The Ly-49A receptor recognizes H-2Dd and H-2Dk.

Application Details

  • Application: IP ; FACS

Handling

  • Format: Liquid
  • Shipping conditions: Shipping at 4°C

Documentation

Related Tools

Product Image

Anti-HPV18E6 [C1N1]

#152765
Product Image

Anti-GCP2 IgG1 (Gamma-tubulin complex component 2) [GPC2-02]

#160570
Product Image

Anti-SDelta3 [7G12]

#152651

References

  • •  Takei et al. 1997. Immunol Rev. 155:67-77. PMID: 9059883.
  • •  Chan et al. 1989. J Immunol. 142(5):1727-36. PMID: 2783949.
  • •  Takei et al. 1983. J Immunol. 130(6):2794-7. PMID: 6304191.