Product Image

Contributor Information

  • Name Fumio Takei
  • Institute BC Cancer

Tool Details

  • Tool name: Anti-CD54 [YN1/1.7.4]
  • Alternate names: ICAM-1
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Mouse
  • Host: Rat
  • Molecular weight of the target: 95 kDa
  • Application: IP ; FACS ; WB
  • Description: CD-54, also known as ICAM-1, is a cell surface glycoprotein expressed on epithelial, lymphocytes, macrophages, dendritic cells, and other immune cells. It plays a role in cellular signalling to stabilize cell-cell interactions and also binds to integrins of type CD11a/CD18 and CD11b/CD18. It has also been shown to be a target for rhinoviruses. This antibody recognizes the murine lymphocyte antigen MALA-2. This antibody inhibits the mixed lymphocyte response and inhibits Con A blasts to MALA-2.This antibody was purified from ascite fluid using ammonium sulfate (50% saturation) precipitation followed by DEAE affi-gel blue chromatography.
  • Immunogen: NS-1 cells
  • Isotype: IgG2b kappa
  • Research area: Immunology; Cancer
  • Myeloma used: Y3

  • For Research Use Only

Target Details

  • Target: CD54
  • Target molecular weight: 95 kDa
  • Target background: CD-54, also known as ICAM-1, is a cell surface glycoprotein expressed on epithelial, lymphocytes, macrophages, dendritic cells, and other immune cells. It plays a role in cellular signalling to stabilize cell-cell interactions and also binds to integrins of type CD11a/CD18 and CD11b/CD18. It has also been shown to be a target for rhinoviruses. This antibody recognizes the murine lymphocyte antigen MALA-2. This antibody inhibits the mixed lymphocyte response and inhibits Con A blasts to MALA-2.This antibody was purified from ascite fluid using ammonium sulfate (50% saturation) precipitation followed by DEAE affi-gel blue chromatography.

Application Details

  • Application: IP ; FACS ; WB

Handling

  • Format: Liquid
  • Shipping conditions: Shipping at 4°C

Documentation

Related Tools

Product Image

Anti-O-linked N-acetylglucosamine (O-GlcNAc) [1E9.E3]

#153894
Product Image

Anti-WFDC5-WAP [M47-P2D5]

#152759
Product Image

Anti-human insulin receptor substrate-1 (IRS-1) [7-72]

#154024

References

  • •  Horley et al. 1989. EMBO J. 8(10):2889-96. PMID: 2573511.
  • •  Takei et al. 1985. J Immunol. 134(3):1403-7. PMID: 2981916.