ANTIBODIES

Contributor Information
- Name Carl G. Figdor
- Institute Radboud University Medical Center (UMC)
Tool Details
- Tool name: Anti-ALCAM AZN-L51 (IgG1) [AZNL51]
- Alternate names: CD166 antigen, MEMD
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: FACS ; IP ; WB
- Description: ALCAM, or CD166, is a cell adhesion molecule that mediates heterotypic cell-cell contacts via its interaction with CD6, resulting in initiation and stabilization of T-cell-dendritic-cell interactions affecting T-cell activation. It also engages in homotypic cell-cell contacts. These ALCAM-ALCAM interactions have been implicated in the development and maintenance of tissue architecture and tumor progression.
- Immunogen: K562-ALCAM
- Isotype: IgG1
- Research area: Cell biology; Cancer; Immunology
- For Research Use Only
Target Details
- Target: Activated leukocyte cell adhesion molecule
- Target background: ALCAM, or CD166, is a cell adhesion molecule that mediates heterotypic cell-cell contacts via its interaction with CD6, resulting in initiation and stabilization of T-cell-dendritic-cell interactions affecting T-cell activation. It also engages in homotypic cell-cell contacts. These ALCAM-ALCAM interactions have been implicated in the development and maintenance of tissue architecture and tumor progression.
Application Details
- Application: FACS ; IP ; WB
Handling
- Format: Liquid
- Shipping conditions: Shipping at 4ðC
References
- • Te Riet et al. 2007. J Cell Sci. 120(Pt 22):3965-76. PMID: 17971418.