ANTIBODIES
Contributor Information
- Name Abdo Alnabulsi
- Institute Vertebrate Antibodies Limited
Tool Details
- Tool name: Anti-AvUCP
- Tool type: Antibodies
- Class: Polyclonal
- Conjugate: Unconjugated
- Reactivity: Avian
- Host: Rabbit
- Molecular weight of the target: 35
- Application: ELISA
- Description: Uncoupling proteins (UCPs) belong to a family of mitochondrial proteins that may cause a leak of protons across the inner membrane, thus uncoupling the oxidation of reduced substrates from the phosphorylation of ADP to ATP. Avian UCP plays a role as a modulator of ROS production in skeletal muscle mitochondria. This antiradical function of avUCP would be of particular importance in preventing cellular damage under hyper metabolism linked to high cellular oxidative activity and a high degree of reduction of the respiratory chain as occurs in hyperthyroidism and chronic exposure to cold. Avian UCP has also been thought to play a role in the control of lipid metabolism but may also confer preventive effects against free radical damage. This AvUCP antibody can be used as a health marker to monitor food intake and body weight.
- Immunogen: Ovalbumin-conjugated synthetic peptide. Peptide immunogen is conserved in all bird species.
- Research area: Cell biology; Immunology
- For Research Use Only
Target Details
- Target: Avian uncoupling protein (AvUCP)
- Target molecular weight: 35
- Target background: Uncoupling proteins (UCPs) belong to a family of mitochondrial proteins that may cause a leak of protons across the inner membrane, thus uncoupling the oxidation of reduced substrates from the phosphorylation of ADP to ATP. Avian UCP plays a role as a modulator of ROS production in skeletal muscle mitochondria. This antiradical function of avUCP would be of particular importance in preventing cellular damage under hyper metabolism linked to high cellular oxidative activity and a high degree of reduction of the respiratory chain as occurs in hyperthyroidism and chronic exposure to cold. Avian UCP has also been thought to play a role in the control of lipid metabolism but may also confer preventive effects against free radical damage. This AvUCP antibody can be used as a health marker to monitor food intake and body weight.
Application Details
- Application: ELISA
Handling
- Format: Liquid
- Storage buffer: Unpurified anti-serum from rabbit preserved in 0.02% Thiomersal
- Storage conditions:
- Shipping conditions: Shipping at 4Ă°C
Documentation
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