ANTIBODIES
Contributor Information
- Name Urpo LamminmĤki
- Institute University of Turku
Tool Details
- Tool name: Anti-GTP [3A5]
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Application: FACS ; IF
- Description: GTPases are central cellular signaling proteins, which cycle between a GDP-bound inactive and a GTP-bound active conformation in a controlled manner. Ras GTPases are frequently mutated in cancer and so far only few experimental inhibitors exist. The most common methods for monitoring GTP hydrolysis rely on luminescent GDP- or GTP-analogs. (From Kopra et al Anal. Chem. 2015, 87, 6, 3527ÄËĂÂĂÂ3534)
- Research area: Cancer; Metabolism
- For Research Use Only
Target Details
- Target: GTP
- Target background: GTPases are central cellular signaling proteins, which cycle between a GDP-bound inactive and a GTP-bound active conformation in a controlled manner. Ras GTPases are frequently mutated in cancer and so far only few experimental inhibitors exist. The most common methods for monitoring GTP hydrolysis rely on luminescent GDP- or GTP-analogs. (From Kopra et al Anal. Chem. 2015, 87, 6, 35273534)
Application Details
- Application: FACS ; IF
Handling
- Format: Liquid
- Shipping conditions: Shipping at 4Ă°C
Documentation
.svg)
Unit size: 
.svg)
.svg)
