ANTIBODIES

Contributor Information
- Institute University of Illinois Chicago
Tool Details
- Tool name: Anti-FoxM1
- Alternate names: FoxM1
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Polyclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Rabbit
- Application: WB ; IP ; ChIP ; ELISA ; IHC
- Description: FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases. Moreover, FOXM1 regulates expression of a large array of G2/M-specific genes, such as Plk1, cyclin B2, Nek2 and CENPF, and plays an important role in maintenance of chromosomal segregation and genomic stability. As a result, FOXM1 is a proto-oncogene associated with basal cell carcinoma.
- Immunogen: His-tagged FoxM1b, 365-748 amino acids
- Research area: Cancer; Cell biology; Drug developement; Genetics
- For Research Use Only
Target Details
- Target: Forkhead Box M1
- Target background: FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases. Moreover, FOXM1 regulates expression of a large array of G2/M-specific genes, such as Plk1, cyclin B2, Nek2 and CENPF, and plays an important role in maintenance of chromosomal segregation and genomic stability. As a result, FOXM1 is a proto-oncogene associated with basal cell carcinoma.
Application Details
- Application: WB ; IP ; ChIP ; ELISA ; IHC
Handling
- Format: Liquid
- Shipping conditions: Shipping at 4ðC
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References
- • Wang et al. 2005. Mol Cell Biol. 25(24):10875-94. PMID: 16314512.