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Contributor Information

  • Institute University of Illinois Chicago

Tool Details

  • Tool name: Anti-FoxM1
  • Alternate names: FoxM1
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Polyclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Rabbit
  • Application: WB ; IP ; ChIP ; ELISA ; IHC
  • Description: FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases. Moreover, FOXM1 regulates expression of a large array of G2/M-specific genes, such as Plk1, cyclin B2, Nek2 and CENPF, and plays an important role in maintenance of chromosomal segregation and genomic stability. As a result, FOXM1 is a proto-oncogene associated with basal cell carcinoma.
  • Immunogen: His-tagged FoxM1b, 365-748 amino acids
  • Research area: Cancer; Cell biology; Drug developement; Genetics

  • For Research Use Only

Target Details

  • Target: Forkhead Box M1
  • Target background: FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases. Moreover, FOXM1 regulates expression of a large array of G2/M-specific genes, such as Plk1, cyclin B2, Nek2 and CENPF, and plays an important role in maintenance of chromosomal segregation and genomic stability. As a result, FOXM1 is a proto-oncogene associated with basal cell carcinoma.

Application Details

  • Application: WB ; IP ; ChIP ; ELISA ; IHC

Handling

  • Format: Liquid
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   Wang et al. 2005. Mol Cell Biol. 25(24):10875-94. PMID: 16314512.