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Contributor Information

  • Institute University of Illinois Chicago

Tool Details

  • Tool name: Anti-ABeta (Abeta) [6C3]
  • Alternate names: AÎ? or Abeta
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: IHC ; WB
  • Description: Defects in APP are associated with the pathology of various types of Alzheimer's disease. Specially, the defective amyloid-beta-APP 40-42 peptides, which MOAB-2 targets exclusively, are major constituents of extracellular plaques and contribute cytotoxic neuronal death.
  • Immunogen: Human beta Amyloid. Recombinant oligomeric A?42. Epitope maps to residues 1-4 of human A?42 and A?40 (DAEF).
  • Research area: Apoptosis and autophagy; Cell biology; Developmental biology

  • For Research Use Only

Target Details

  • Target: Amyloid-? Peptide
  • Target background: Defects in APP are associated with the pathology of various types of Alzheimer's disease. Specially, the defective amyloid-beta-APP 40-42 peptides, which MOAB-2 targets exclusively, are major constituents of extracellular plaques and contribute cytotoxic neuronal death.

Application Details

  • Application: IHC ; WB

Handling

  • Format: Liquid
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  295587871
  • •  Fekete et al. 2019. Neuroscience. 405:35-46. PMID: 29522854.
  • •  Scaringi et al. 2012. Anticancer Res. 32(10):4213-23. PMID: 23060541.
  • •  Youmans et al. 2012. Mol Neurodegener. 7:8. PMID: 22423893.
  • •  Youmans et al. 2012. Mol Neurodegener. 7:8. PMID: 22423893.