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Contributor Information

  • Institute Absolute Antibody ; University of Oxford

Tool Details

  • Tool name: Anti-CD68 [Y-2/131/47] rAb
  • Alternate names: CD68 Molecule; CD68 Antigen; Macrophage Antigen CD68; GP11; Scavenger Receptor Class D; Member; Scavenger Receptor Class D; SCARD1; LAMP4
  • Clone: Y-2/131/47
  • Tool type: Antibodies
  • Class: Recombinant
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Description: CD68 is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. CD68 is a member of a family of hematopoietic mucin-like molecules that includes leukosialin/CD43 and stem cell antigen CD34.
  • Immunogen: Phytohaemagglutinin-activated peripheral blood mononuclear cells
  • Isotype: IgG1
  • Research area: Cell biology; Immunology; Stem cell biology

  • For Research Use Only

Target Details

  • Target: CD68
  • Target background: CD68 is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. CD68 is a member of a family of hematopoietic mucin-like molecules that includes leukosialin/CD43 and stem cell antigen CD34.

Application Details

Handling

  • Format: Liquid
  • Storage buffer: PBS (0.1M) + 0.5M imidazole at pH 7.4. This product was purified using affinity chromatography (protein A)
  • Storage conditions:
  • Shipping conditions: Shipping at 4° C

Documentation

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References

  • •  A human macrophage-associated antigen (CD68) detected by six different monoclonal antibodies.
  • •  CD68 reactivity of non-macrophage derived tumours in cytological specimens.
  • •  Distribution of the CD68 macrophage/myeloid associated antigen.
  • •  Doussis et al. 1993. J Clin Pathol. 46(4):334-6. PMID: 7684403.
  • •  KP1: a new monoclonal antibody that detects a monocyte/macrophage associated antigen in routinely processed tissue sections.
  • •  Micklem et al. 1989. Br J Haematol. 73(1):6-11. PMID: 2803980.
  • •  Pulford et al. 1989. J Clin Pathol. 42(4):414-21. PMID: 2654191.
  • •  Pulford et al. 1990. Int Immunol. 2(10):973-80. PMID: 2078523.