ANTIBODIES
Contributor Information
- Name Peter Krieg
- Institute Deutsches Krebsforschungszentrum (DKFZ)- German Cancer Research Center
Tool Details
- Tool name: Anti-12R-LOX
- Alternate names: Arachidonate 12-lipoxygenase, 12R-type, 12R-LOX, 12R-lipoxygenase, Epidermis-type lipoxygenase 12. UniProt ID:O75342
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Polyclonal
- Conjugate: Unconjugated
- Reactivity: Human ; Mouse
- Host: Rabbit
- Application: WB
- Description: Alox12b plays a crucial role in the synthesis of corneocytes lipid envelope and the establishment of the skin barrier to water loss. Ichthyosis is a family of rare genetic skin disorders characterised by dry, thickened, scaly skin associated with mutations in Alox12b.
- Immunogen: Mouse 12R-LOX (Y14334) Peptide Y1: aa 159-179 IPSYHPPPRRCRNPNRPEWDG Or Mouse 12R-LOX (Y14334) Peptide Y2: aa 167-189 CRNPNRPEWDGYIPGFPILINIKA
- Research area: Cell biology; Metabolism
- For Research Use Only
Target Details
- Target: Arachidonate 12-lipoxygenase (ALOX12B)
- Target background: Alox12b plays a crucial role in the synthesis of corneocytes lipid envelope and the establishment of the skin barrier to water loss. Ichthyosis is a family of rare genetic skin disorders characterised by dry, thickened, scaly skin associated with mutations in Alox12b.
Application Details
- Application: WB
Handling
- Format: Liquid
- Storage buffer: Neat sera
- Shipping conditions: Shipping at 4Ă°C
Documentation
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