ANTIBODIES
Contributor Information
- Name Martin Humphries
- Institute University of Manchester ; Absolute Antibody
Tool Details
- Tool name: Anti-CD151 [11G5a]
- Alternate names: CD151 Molecule (Raph Blood Group); Platelet-Endothelial Tetraspan Antigen; CD151 Antigen (Raph Blood Group); Membrane Glycoprotein SFA-1; Tetraspanin-24; CD151 Antigen; Tspan-24; TSPAN24; PETA-3
- Clone: r11G5a
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Recombinant
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Cancer type: Broadly Applicable
- Application: ELISA ; FACS ; IHC ; IF ; IP ; WB
- Description: Clone 11G5a recognizes the human CD151 cell surface antigen, also known as PETA-3.
- Isotype: IgG1
- Research area: Cell biology; Cancer; Tissue-specific biology; Cell signaling and signal transduction; Immunology
- For Research Use Only
Target Details
- Target: CD151 (PETA-3)
- Target background: CD151 is expressed by epithelial cells, endothelial cells, platelets, megakaryocytes, monocytes and in the renal glomeruli and proximal and distal tubules. CD151 is not expressed by lymphocytes or granulocytes. More recently CD151 has also been shown to be expressed by erythrocytes, and to carry the MER2 blood group antigen. CD151 is a cell surface glycoprote involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells.
Application Details
- Application: ELISA ; FACS ; IHC ; IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS
- Shipping conditions: Shipping at 4Ă°C
Documentation
Related Tools
References
- • Original hybridoma first published in: Yauch et al. 1998. Mol Biol Cell. 9(10):2751-65. PMID: 9763442.
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