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Contributor Information

  • Name Ayham Alnabulsi
  • Institute Vertebrate Antibodies Limited

Tool Details

  • Tool name: Anti-CD3 [T1P1D4*C6]
  • Alternate names: CD3, CD3gd, cd3g/d, cd3-gamma
  • Clone: T1P1D4*C6
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Salmon ; Rainbow Trout
  • Host: Mouse
  • Application: ELISA ; FACS ; IHC ; WB
  • Strain: Balb/c
  • Description: Monoclonal antibody specific for CD3 in Atlantic salmon and rainbow trout. Background and Research Application The CD3 complex, composed of four distinct CD3 polypeptide chains (CD3?, CD3? and 2X CD3?), associates with the T cell antigen receptor (TCR). It is found on all mature human T lymphocytes, NK cells and some thymocytes. CD3 is a member of the immunoglobulin superfamily, involved in antigen recognition, T lymphocyte activation and signal transduction. Anti-CD3 [T1P1D4*C6] is specific for CD3 in Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss).
  • Immunogen: Ovalbumin-conjugated synthetic peptide- TLEYKDENTNEY
  • Immunogen UniProt ID: A3RK68
  • Isotype: IgG1 kappa
  • Research area: Cancer; Cell biology; Cell signaling and signal transduction; Immunology; Stem cell biology
  • Myeloma used: P3X63Ag8.653

  • For Research Use Only

Target Details

  • Target: T-cell surface glycoprotein CD3 gammadelta-A chain
  • Target background: Monoclonal antibody specific for CD3 in Atlantic salmon and rainbow trout. Background and Research Application The CD3 complex, composed of four distinct CD3 polypeptide chains (CD3?, CD3d and 2X CD3), associates with the T cell antigen receptor (TCR). It is found on all mature human T lymphocytes, NK cells and some thymocytes. CD3 is a member of the immunoglobulin superfamily, involved in antigen recognition, T lymphocyte activation and signal transduction. Anti-CD3 [T1P1D4*C6] is specific for CD3 in Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss).

Application Details

  • Application: ELISA ; FACS ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: Store at -20°C frozen. Avoid repeated freeze / thaw cycles
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Immunohistochemical examination of immune cells in adipose tissue of rainbow trout (Oncorhynchus mykiss) following intraperitoneal vaccination. Veenstra et al. 2019. Fish Shellfish Immunol. 87:559-564. PMID: 30731214.
  • •  Immunohistochemical examination of immune cells in adipose tissue of rainbow trout (Oncorhynchus mykiss) following intraperitoneal vaccination.