ANTIBODIES

Contributor Information
- Name Margaret Goodall
- Institute University of Birmingham
Tool Details
- Tool name: Anti-CD44 [BU93]
- Alternate names: Cell differentiation 44; Homing cell adhesion molecule; HCAM; phagocytic glycoprotein-1; Pgp-1; Hermes antigen; lymphocyte homing receptor; ECM-III; HUTCH-1.
- Clone: BU93
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: IHC
- Strain: Balb/c
- Description: The CD44 antigen is a cell-surface glycoprotein involved in cell to cell and cell-matrix interactions, cell adhesion and migration, which it achieves through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes.
- Isotype: IgG1
- Research area: Cell biology; Cancer; Cell signaling and signal transduction; Immunology
- For Research Use Only
Target Details
- Target: CD44
- Target background: The CD44 antigen is a cell-surface glycoprotein involved in cell to cell and cell-matrix interactions, cell adhesion and migration, which it achieves through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes.
Application Details
- Application: IHC
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15ðC to -25ðC
- Shipping conditions: Shipping at 4ðC
Related Tools
References
- • Leucocyte Typing IV, (1989): edited by W. Knapp, OUP, Oxford.
- • Leucocyte Typing V, (1995): edited by S.F. Schlossman, OUP, Oxford.
- • Leucocyte Typing VII, (2002): edited by D.Y. Mason, OUP, Oxford.