ANTIBODIES
Contributor Information
- Name Margaret Goodall
- Institute University of Birmingham
Tool Details
- Tool name: Anti-Germinal Centre macrophages [BU83]
- Alternate names: PB33
- Clone: BU83
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: IHC
- Strain: Balb/c
- Description: Macrophages are a type of white blood cell which through a process called phagocytosis engulfs and digests cellular debris, foreign substances, microbes, cancer cells. They can be found in all tissues where they play a critical role in the innate immune system and also help initiate adaptive immunity through recruiting lymphocytes and other immune cells. Germinal centres are sites within secondary lymph nodes where mature B lymphocytes proliferate, differentiate and mutate their antibody genes, enabling switching of their class of antibody during the course of infection.
- Immunogen: Pre-B cells
- Isotype: IgG2a
- Research area: Immunology
- For Research Use Only
Target Details
- Target: Macrophages
- Target background: Macrophages are a type of white blood cell which through a process called phagocytosis engulfs and digests cellular debris, foreign substances, microbes, cancer cells. They can be found in all tissues where they play a critical role in the innate immune system and also help initiate adaptive immunity through recruiting lymphocytes and other immune cells. Germinal centres are sites within secondary lymph nodes where mature B lymphocytes proliferate, differentiate and mutate their antibody genes, enabling switching of their class of antibody during the course of infection.
Application Details
- Application: IHC
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15Ă°C to -25Ă°C
- Shipping conditions: Shipping at 4Ă°C
Documentation
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