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Contributor Information

  • Name Nancy Hogg
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-S100A9 [NH3]
  • Alternate names: MRP-14, calgranulin B
  • Clone: NH3
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Polyclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Rabbit
  • Molecular weight of the target: 14 kDa
  • Application: IHC ; WB
  • Description: S100A9, together with heterodimeric partner S100A8, is a major biomarker of inflammation both in released form in serum and through increased expression in epithelial tissue and in many tumours.
  • Immunogen: Recombinant human S100-A9 (MRP-14)
  • Research area: Cancer; Cell signaling and signal transduction; Immunology

  • For Research Use Only

Target Details

  • Target: S100A9
  • Target molecular weight: 14 kDa
  • Target background: S100A9, together with heterodimeric partner S100A8, is a major biomarker of inflammation both in released form in serum and through increased expression in epithelial tissue and in many tumours.

Application Details

  • Application: IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: Whole serum
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Robinson et al. 2002. J Biol Chem. 277(5):3658-65. PMID: 11723110.
  • •  The S100 family heterodimer, MRP-8/14, binds with high affinity to heparin and heparan sulfate glycosaminoglycans on endothelial cells.
  • •  Robinson et al. 2000. Biochem Biophys Res Commun. 275(3):865-70. PMID: 10973813.
  • •  A comparison of human S100A12 with MRP-14 (S100A9).