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Contributor Information

  • Name Ayham Alnabulsi
  • Institute Vertebrate Antibodies Limited

Tool Details

  • Tool name: Anti-Cytochrome P450 2J2 [Z9P1G9*A2]
  • Alternate names: Arachidonic acid epoxygenase, CYPIIJ2
  • Clone: Z9P1G9* A2
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target: 58 kDa
  • Application: ELISA ; IHC ; WB
  • Strain: Balb/c
  • Description: Cytochrome P450 2J2 metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools. Highly expressed in heart, present at lower levels in liver, ileum, jejunum, colon, and kidney. Localised to the endoplasmic reticulum membrane; microsome membrane.
  • Immunogen: Ovalbumin-conjugated synthetic peptide KFTFRPPNNE (C-terminal sequence)
  • Isotype: IgG
  • Research area: Cancer; Tissue-specific biology; Cell signaling and signal transduction; Metabolism
  • Myeloma used: P3X63Ag8.653

  • For Research Use Only

Target Details

  • Target: Cytochrome P450, family 2, subfamily J, polypeptide 2 (CYP2J2)
  • Target molecular weight: 58 kDa
  • Target background: Cytochrome P450 2J2 metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools. Highly expressed in heart, present at lower levels in liver, ileum, jejunum, colon, and kidney. Localised to the endoplasmic reticulum membrane; microsome membrane.

Application Details

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -20°C
  • Shipping conditions: Shipping at 4°C

Documentation