ANTIBODIES

Contributor Information
- Name Ayham Alnabulsi
- Institute Vertebrate Antibodies Limited
Tool Details
- Tool name: Anti-sCD40 (soluble) [T8P2G4*A6] mAb
- Alternate names: CD4 Molecule; CD4L Receptor; TNFRSF5; CDW4; Bp5; Tumor Necrosis Factor Receptor Superfamily; Member; B Cell Surface Antigen CD4; CD4 Antigen; P5
- Clone: T8P2G4*A6
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Molecular weight of the target: 22 kDa
- Application: ELISA ; IHC ; WB
- Description: CD40 is a 48 kD type I glycoprotein and a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.
- Immunogen: Ovalbumin-conjugated synthetic peptide RDPVCHPLGA (C-terminal sequence)
- Isotype: IgG2b kappa
- Research area: Cancer; Cell signaling and signal transduction
- For Research Use Only
Target Details
- Target: CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40 soluble form)
- Target molecular weight: 22 kDa
- Target background: CD40 is a 48 kD type I glycoprotein and a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.
Application Details
- Application: ELISA ; IHC ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C