Product Image

Contributor Information

  • Name Ayham Alnabulsi
  • Institute Vertebrate Antibodies Limited

Tool Details

  • Tool name: Anti-TCPb [F39P7F11]
  • Clone: F39 P7 F11
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human ; Mouse ; Rat ; Xenopus laevis ; Salmon
  • Host: Mouse
  • Application: ELISA ; IHC ; WB
  • Strain: Balb/c
  • Description: The chaperonins are key molecular complexes, which are essential in the folding of proteins to produce stable and functionally competent protein conformations. One member of the chaperonin group of proteins is TCP1 (chaperonin containing t-complex polypeptide 1, or CCT), but little is known about this protein in tumours.
  • Immunogen: C-terminal peptide with sequence RKRVPDHHPC conjugated to ovalbumin
  • Isotype: IgG2a kappa
  • Research area: Apoptosis and autophagy; Cancer; Cell biology
  • Myeloma used: P3X63Ag8.653

  • For Research Use Only

Target Details

  • Target: T-complex protein 1, beta subunit
  • Target background: The chaperonins are key molecular complexes, which are essential in the folding of proteins to produce stable and Fnly competent protein conformations. One member of the chaperonin group of proteins is TCP1 (chaperonin containing t-complex polypeptide 1, or CCT), but little is known about this protein in tumours.

Application Details

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

Related Tools

Product Image

Anti-miniSOG [3A11a]

#161723
Product Image

Anti-MAP2ab IgGM (Microtubule Associated Protein 2ab) [MT-02]

#160571
Product Image

Anti-hCAP-18 [H7]

#154141

References

  • •  Coghlin et al. 2006. J Pathol. 210(3):351-7. PMID: 16981251.
  • •  Characterization and over-expression of chaperonin t-complex proteins in colorectal cancer.