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Contributor Information

  • Name Ayham Alnabulsi
  • Institute Vertebrate Antibodies Limited

Tool Details

  • Tool name: Anti-Cytochrome P450 3A5 [F18P3B6]
  • Clone: F18P3B6
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: IHC ; WB ; ELISA ; IHC ; WB
  • Strain: Balb/c
  • Description: This monoclonal antibody (MAb), when used in conjunction with the MAb specific to CYP3A7 clone F19 P2 H2, is able to differentiate between the CYP450 family 3 members: CYP3A5 and CYP3A7.
  • Immunogen: Ovalbumin-conjugated synthetic peptide DSRDGTLSGE (C-terminal sequence)
  • Isotype: IgG1 kappa
  • Research area: Cancer; Tissue-specific biology; Cell signaling and signal transduction; Metabolism
  • Myeloma used: P3X63Ag8.653

  • For Research Use Only

Target Details

  • Target: CYP3A5- Cytochrome P450 3A5 (EC 1.14.14.1) (niphedipine oxidase), (CYPIIIA5) (P450-PCN3) (HLp2).
  • Target background: This monoclonal antibody (MAb), when used in conjunction with the MAb specific to CYP3A7 clone F19 P2 H2, is able to differentiate between the CYP450 family 3 members: CYP3A5 and CYP3A7.

Application Details

  • Application: IHC ; WB ; ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Zia et al. 2015. Int J Exp Pathol. 96(2):81-6. PMID: 25670065.
  • •  CYP3A isoforms in Ewing's sarcoma tumours: an immunohistochemical study with clinical correlation.
  • •  Murray et al. 2010. Histopathology. 57(2):202-11. PMID: 20716162.
  • •  Profiling the expression of cytochrome P450 in breast cancer.
  • •  Downie et al. 2005. Clin Cancer Res. 11(20):7369-75. PMID: 16243809.
  • •  Profiling cytochrome P450 expression in ovarian cancer: identification of prognostic markers.
  • •  Kumarakulasingham et al. 2005. Clin Cancer Res. 11(10):3758-65. PMID: 15897573.
  • •  Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis.
  • •  Kosik et al. 1992. Science. 256(5058):780-3. PMID: 1589757.
  • •  Alzheimer's disease: a cell biological perspective.