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Contributor Information

  • Name Colin Brooks
  • Institute Newcastle University

Tool Details

  • Tool name: Anti-NKRP1D [4E9]
  • Alternate names: Killer Cell Lectin Like Receptor B1; Natural Killer Cell Surface Protein P1A; C-Type Lectin Domain Family 5 Member B; HNKR-P1A; CLEC5B; NKRP1A; CD161 Antigen; NKR
  • Clone: 4.00E+09
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Mouse
  • Host: Rat
  • Application: Fn
  • Description: The 4E9 antibody binds to the mouse C57 NKRP1D (CD161b/d) receptor with very low cross reactivity on NKRP1A, NKRP1C, and possibly NKRP1F transfectants. It may bind to NKRP1 molecules in other strains but this has not been investigated in detail. Note that this mAb shows weaker staining than the 2D9 NKRP1D mAb (Cat #151814), but has higher activity in functional assays.
  • Immunogen: YB2/0 rat plasmacytoma cells transfected with NKRP1
  • Isotype: IgG3 kappa
  • Research area: Cell biology
  • Myeloma used: NS0

  • For Research Use Only

Target Details

  • Target: NKRP1D
  • Target background: The 4E9 antibody binds to the mouse C57 NKRP1D (CD161b/d) receptor with very low cross reactivity on NKRP1A, NKRP1C, and possibly NKRP1F transfectants. It may bind to NKRP1 molecules in other strains but this has not been investigated in detail. Note that this mAb shows weaker staining than the 2D9 NKRP1D mAb (Cat #151814), but has higher activity in functional assays.

Application Details

  • Application: Fn

Handling

  • Format: Liquid
  • Concentration: 1mg/ml
  • Storage buffer: DMEM, 5 x10 5 M 2 ME, and 10% FBS
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Aust et al., 2009. J. Immunol. 183:106-16. PMID: 19535641