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Contributor Information

  • Name Mary Collins
  • Institute University College London (UCL)

Tool Details

  • Tool name: Anti-vFlip [6/14]
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Rat
  • Application: WB ; IHC; IP ; WB
  • Description: v-FLIP synthesis can be up-regulated when apoptosis is triggered. It may provide a survival advantage for KSHV-infected cells under some circumstances and could be a reason for an IRES-dependent translation of v-FLIP. This antibody can be used to detect expression of latent vFLIP in KSHV infected cells and tumours and for examining the role of vFLIP in cell signaling.
  • Immunogen: Full-length recombinant v-FLIP expressed in Escherichia coli
  • Isotype: IgG
  • Research area: Apoptosis and autophagy; Cell biology; Microbiology

  • For Research Use Only

Target Details

  • Target: vFlip
  • Target background: v-FLIP synthesis can be up-regulated when apoptosis is triggered. It may provide a survival advantage for KSHV-infected cells under some circumstances and could be a reason for an IRES-dependent translation of v-FLIP. This antibody can be used to detect expression of latent vFLIP in KSHV infected cells and tumours and for examining the role of vFLIP in cell signaling.

Application Details

  • Application: WB ; IHC; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Low et al. 2001. J Virol. 75:2938-45 PMID: 11222719 Field et al. 2003. J Cell Sci. 116(Pt 18):3721-8. PMID: 12890756