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Contributor Information

  • Name Julian Gannon
  • Institute Cancer Research UK, London Research Institute: Clare Hall Laboratories

Tool Details

  • Tool name: Anti-Phospho-cdc20 (Thr79) [BT2.1]
  • Alternate names: APC/C activator protein CDC2; Cell division control protein 2; YGL116W; Cell Division Cycle 2; P55CDC; CDC2 Cell Division Cycle 2 Homolog; Cell Division Cycle 2 Homolog; BA276H19.3; CDC2A
  • Clone: BT2.1
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Xenopus laevis
  • Host: Mouse
  • Molecular weight of the target: 55 kDa
  • Application: ELISA ; WB
  • Description: Cdc20 (fizzy protein) is associated with the activation of the anaphase-promoting complex at the onset of anaphase. Cdc20 is phosphorylated during mitosis so this epitope is a good marker of cell cycle progression
  • Immunogen: GPKMQGpTPSRAG. pT represents phosphorylated Thr79.
  • Isotype: Not Known
  • Research area: Cell biology
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: cdc20
  • Target molecular weight: 55 kDa
  • Target background: Cdc20 (fizzy protein) is associated with the activation of the anaphase-promoting complex at the onset of anaphase. Cdc20 is phosphorylated during mitosis so this epitope is a good marker of cell cycle progression

Application Details

  • Application: ELISA ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Labit et al. 2012. EMBO J. 31(15):3351-62. PMID: 22713866.
  • •  Dephosphorylation of Cdc20 is required for its C-box-dependent activation of the APC/C.