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Contributor Information

  • Name Jenny Southgate ; Ludwik Trejdosiewicz
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-Keratin 19 [LAS86]
  • Clone: LAS86
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target: 40 kDa
  • Application: IHC
  • Description: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 19 restricted 'in situ' to differentiated urothelium. Useful in the studies of epithelial cells and tumor origin.
  • Isotype: IgM
  • Research area: Cell signaling and signal transduction

  • For Research Use Only

Target Details

  • Target: Cytokeratin 19
  • Target molecular weight: 40 kDa
  • Target background: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 19 restricted 'in situ' to differentiated urothelium. Useful in the studies of epithelial cells and tumor origin.

Application Details

  • Application: IHC

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Trejdosiewicz et al. 1988. Struct Funct Cytoskel. 171: 265-271
  • •  von Koskull et al. 1984. Hum Genet. 65(3):262-7. PMID: 6199284.
  • •  Identification of cells from fetal bladder epithelium in human amniotic fluid.