ANTIBODIES

Contributor Information
- Institute Marie Curie Research Institute
Tool Details
- Tool name: Anti-ACF1 [hACF1 BAZIA]
- Clone: hACF1 BAZIA
- Tool type: Antibodies
- Tool sub-type: Primary Antibody
- Class: Polyclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Rabbit
- Molecular weight of the target: 179 kDa
- Application: WB
- Description: hACF1/BAZIA is a subunit of the ATP-dependent chromatin-remodelling factor (ACF) complex, and the ISWI CHRAC remodelling complex. In the ACF complex, hACF1/BAZIA influences the nucleosome remodelling activity of the SNF2h ATPase. In the CHRAC complex, hACF1/BAZIA is thought to target CHRAC to heterochromatin. hACF1/BAZIA has several conserved domains including a bromodomain, BAZ, PHD finger, WAC, and WAKZ.
- Immunogen: Human peptide conjugated to LPH (hemocyanine from Limulus polyphemus)
- Research area: Genetics
- For Research Use Only
Target Details
- Target: ATP-utilizing chromatin assembly and remodeling factor 1 (ACF1; BAZIA)
- Target molecular weight: 179 kDa
- Target background: hACF1/BAZIA is a subunit of the ATP-dependent chromatin-remodelling factor (ACF) complex, and the ISWI CHRAC remodelling complex. In the ACF complex, hACF1/BAZIA influences the nucleosome remodelling activity of the SNF2h ATPase. In the CHRAC complex, hACF1/BAZIA is thought to target CHRAC to heterochromatin. hACF1/BAZIA has several conserved domains including a bromodomain, BAZ, PHD finger, WAC, and WAKZ.
Application Details
- Application: WB
Handling
- Format: Liquid
- Concentration: 1.5 mg/ml
- Storage buffer: Tris-Glycine buffer, pH7.5, 250mM NaCl
- Storage conditions: -15ðC to -25ðC
- Shipping conditions: Shipping at 4ðC
Related Tools
References
- • Poot et al. 2000. EMBO J. 19(13):3377-87. PMID: 10880450.
- • HuCHRAC, a human ISWI chromatin remodelling complex contains hACF1 and two novel histone-fold proteins.