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Contributor Information

  • Institute University of Birmingham

Tool Details

  • Tool name: Anti-CD72 [BU41]
  • Alternate names: CD72 Molecule; CD72 Antigen; Lyb-2; CD72b; LYB2
  • Clone: BU41
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human ; Mouse
  • Host: Mouse
  • Application: ELISA ; FACS
  • Strain: Balb/c
  • Description: CD72, a member of the C-type lectin superfamily, is a 45 kDa type II transmembrane glycoprotein. It is expressed from the pro-B through to the mature B cell stage but absent in terminally differentiated plasma cells. Ligation of CD72 enhances B cell growth and proliferation.
  • Isotype: IgM
  • Research area: Immunology; Stem cell biology
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: CD72
  • Target background: CD72, a member of the C-type lectin superfamily, is a 45 kDa type II transmembrane glycoprotein. It is expressed from the pro-B through to the mature B cell stage but absent in terminally differentiated plasma cells. Ligation of CD72 enhances B cell growth and proliferation.

Application Details

  • Application: ELISA ; FACS

Handling

  • Format: Liquid
  • Concentration: 1mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Knapp W. et al. 1989. Leukocyte Typing IV. Oxford University Press. ISBN-13: 978-0192618672
  • •  Hollenbaugh et al. 1992. EMBO J. 11(12):4313-21. PMID: 1385114.
  • •  The human T cell antigen gp39, a member of the TNF gene family, is a ligand for the CD40 receptor: expression of a soluble form of gp39 with B cell co-stimulatory activity.
  • •  Luo et al. 1992. J Immunol. 148(6):1630-4. PMID: 1371783.
  • •  Ly-1 (CD5), a membrane glycoprotein of mouse T lymphocytes and a subset of B cells, is a natural ligand of the B cell surface protein Lyb-2 (CD72).