Product Image

Contributor Information

  • Institute University of Birmingham

Tool Details

  • Tool name: Anti-LewisX [BU60]
  • Alternate names: Fucosyltransferase 4; Galactoside 3-L-Fucosyltransferase; ELAM-1 Ligand Fucosyltransferase; FUC-TIV; FCT3A; ELFT; Stage-Specific Embryonic Antigen; Alpha (1,3) Fucosyltransferase; EC 2.4.1.65; Lewis X; SSEA-1; FUTIV; CD15; LeX
  • Clone: BU60
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; FACS ; IHC ; IP ; Fn ; WB
  • Strain: Balb/c
  • Description: Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias and is commonly used in the diagnosis of Hodgkin’s disease. It can also be used for analysis of myeloid leukaemias and studies of myeloid differentiation.
  • Isotype: IgM
  • Research area: Cancer; Immunology
  • Myeloma used: P3/NS1/1-Ag4.1

  • For Research Use Only

Target Details

  • Target: Lewis X (CD15)
  • Target background: Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias and is commonly used in the diagnosis of Hodgkin's disease. It can also be used for analysis of myeloid leukaemias and studies of myeloid differentiation.

Application Details

  • Application: ELISA ; FACS ; IHC ; IP ; Fn ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   Kishimoto T.Leucocyte Typing V1. 1998. Garland Publishing, NY.
  •   Carter et al. 1999. Xenotransplantation. 6(2):123-30. PMID: 10431789.
  •   Cross-species reactivity of a panel of antibodies with monkey and porcine tissue.
  •   Zhang et al. 1998. Hybridoma. 17(5):445-56. PMID: 9873990.
  •   Novel monoclonal antibodies to putative selectin carbohydrate ligands that inhibit selectin binding to myeloid cells.