ANTIBODIES
Contributor Information
- Institute University of Birmingham
Tool Details
- Tool name: Anti-LewisX [BU28]
- Alternate names: Fucosyltransferase 4; Galactoside 3-L-Fucosyltransferase; ELAM-1 Ligand Fucosyltransferase; FUC-TIV; FCT3A; ELFT; Stage-Specific Embryonic Antigen; Alpha (1,3) Fucosyltransferase; EC 2.4.1.65; Lewis X; SSEA-1; FUTIV; CD15; LeX
- Clone: BU28
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: FACS
- Strain: Balb/c
- Description: Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias and is commonly used in the diagnosis of HodgkinÄËĂÂĂÂs disease. It can also be used for analysis of myeloid leukaemias and studies of myeloid differentiation.
- Isotype: IgM
- Research area: Cancer; Immunology
- Myeloma used: P3/NS1/1-Ag4.1
- For Research Use Only
Target Details
- Target: Lewis X (CD15)
- Target background: Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias and is commonly used in the diagnosis of Hodgkin's disease. It can also be used for analysis of myeloid leukaemias and studies of myeloid differentiation.
Application Details
- Application: FACS
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15Ă°C to -25Ă°C
- Shipping conditions: Shipping at 4Ă°C
Documentation
Related Tools
References
- • Knapp et al. 1989. Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, Oxford.
- • Zhang et al. 1998. Hybridoma. 17(5):445-56. PMID: 9873990.
- • Novel monoclonal antibodies to putative selectin carbohydrate ligands that inhibit selectin binding to myeloid cells.
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