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Contributor Information

  • Institute University of Birmingham

Tool Details

  • Tool name: Anti-CD9 [BU16]
  • Clone: BU16
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC ; IF ; IP ; WB
  • Strain: Balb/c
  • Description: CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and neurons and glial cells in the peripheral nervous system. CD9 mediates platelet aggregation and activation via FCGR2a. It may play a role in cell migration.
  • Isotype: IgG2a
  • Research area: Cell biology; Immunology
  • Myeloma used: P3/NS1/1-Ag4.1

  • For Research Use Only

Target Details

  • Target: CD9
  • Target background: CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and neurons and glial cells in the peripheral nervous system. CD9 mediates platelet aggregation and activation via FCGR2a. It may play a role in cell migration.

Application Details

  • Application: FACS ; IHC ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Takeda et al. 2003. J Cell Biol. 161(5):945-56. PMID: 12796480.
  • •  Tetraspanins CD9 and CD81 function to prevent the fusion of mononuclear phagocytes.
  • •  Funakoshi et al. 2003. Oncogene. 22(5):674-87. PMID: 12569360.
  • •  Expression of tetraspanins in human lung cancer cells: frequent downregulation of CD9 and its contribution to cell motility in small cell lung cancer.
  • •  Flora et al. 1994. Eur J Immunol. 24(11):2625-32. PMID: 7525298.
  • •  Recognition of apoptotic cells by human macrophages: inhibition by a monocyte/macrophage-specific monoclonal antibody.