Product Image

Contributor Information

  • Name Roy Jefferis
  • Institute University of Birmingham

Tool Details

  • Tool name: Anti-Leu2 [BU88]
  • Clone: BU88
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC
  • Strain: Balb/c
  • Description: BU88 may be used for the detection of immunoregulatory T cell subset imbalance in autoimmune and immunodeficiency states, categorisation of T cell acute lymphoblastic leukaemia and lymphoblastic lymphoma and T4/T8 ratios in rheumatoid arthritis, multiple sclerosis, etc.
  • Immunogen: CD8 enriched peripheral blood lymphocytes
  • Isotype: IgG1
  • Research area: Immunology; Stem cell biology
  • Myeloma used: P3/NS1/1-Ag4.1

  • For Research Use Only

Target Details

  • Target: Leu2 (CD8)
  • Target background: Leu-2 is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. Leu-2 is present on human suppressor / cytotoxic T cells, 30% of circulating T cells.

Application Details

  • Application: FACS ; IHC

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

Related Tools

Product Image

Anti-CD9 [P1/33/2] rAb

#154820
Product Image

Anti-S100A9 [1H9]

#151216
Product Image

Anti-LKAAEAR1 [Z36P2C1*E7]

#152764

References

  • •  Kishimoto T. et al. (Eds.) 1997. Leukocyte Typing VI. Garland Publishing Inc. ISBN-13: 978-0815327455
  • •  Leukocyte Typing VI. Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997)
  • •  Langermans et al. 2000. J Med Primatol. 29(6):397-401. PMID: 11168830.
  • •  Reactivity of human T-lymphocyte-specific antibodies with peripheral blood mononuclear cells and spleen of Aotus azarae ssp. boliviensis (owl monkey).